Fig 1. Biochemical progression-free survival stratified by preoperative PSA
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Chromogranin A and biochemical progression-free survival in prostate adenocarcinomas submitted to radical prostatectomy.
The primary aim of the present study was to determine the prognostic role of elevated levels of chromogranin A (CgA) in terms of biochemical prostate-specific antigen (PSA) progression after radical prostatectomy (RRP) for prostate adenocarcinoma. Two hundred and sixty-four consecutive men with non-metastatic prostate adenocarcinoma submitted to RRP represented our population. In all cases, a b...
متن کاملPrognostic value of surgical margin status for biochemical recurrence following radical prostatectomy.
OBJECTIVE We evaluated the preoperative parameters to predict a positive surgical margin (SM) at radical prostatectomy for patients with prostate cancer. In addition, the prognostic factors for biochemical recurrence were determined in patients with positive SMs. METHODS We retrospectively analysed 238 patients with prostate cancer who underwent retropubic radical prostatectomy and bilateral ...
متن کاملPSA mass as a marker of prostate cancer progression after radical prostatectomy
BACKGROUND Obese patients with prostate cancer may have lower preoperative PSA concentration due to hemodilution. Lower PSA concentration may falsely affect assessing the risk of progression after radical prostatectomy (RP). The aim of this study was to determine preoperative PSA mass as the absolute amount of PSA protein secreted into circulation, and evaluation of its usefulness in prediction...
متن کاملOutcome of surgery in locally advanced pT3a prostate cancer
INTRODUCTION The aim of this study is to present the oncologic outcomes and to determine prognostic parameters of overall (OS), cancer specific survival (CSS), disease progression free survival (DPFS) and biochemical progression free survival (BPFS) after surgery for pT3a prostate cancer (PCa). MATERIAL AND METHODS Between 2002 and 2007, a pT3a stage after radical prostatectomy was detected i...
متن کاملImpact of positive surgical margins after radical prostatectomy.
The aim of our study was to evaluate the impact of margin positivity in clinically and pathologically localized prostate cancer (pT2) after radical prostatectomy on biochemical recurrence and time to adjuvant treatment. We analyzed data from 371 patients who underwent radical prostatectomy. At the mean follow up of 36 (25-54) months, impact of margin positivity in pT2 patients on prostate speci...
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